• A balanced and synergistic blend of methylation-supportive B vitamins
• Provides the externally methylated forms of folate and vitamin B12
• Activated forms of vitamin B2 and B6 provide crucial co-factor support for the proper metabolism of folate, B12 and methylation
• May provide a therapeutic dose of choline for support of the alternate BHMT homocysteine methylation pathway
• May help to support the maintenance of normal, healthy homocysteine levels via remethylation back to methionine
• Provides vitamin B6 for conversion of homocysteine to cysteine via the transulfation pathway
• May support the synthesis of glutathione
• Vitamin B2 is a component of glutathione reductase and a crucial cofactor in the activity of MTHFR
• Choline may support normal lipid metabolism
• Choline may assists in the synthesis of SAMe
• Choline serves as a valuable precursor for the synthesis of acetylcholine and phosphatidylcholine

Ingredients

Excipients: Leucine, Microcrystalline Cellulose, Tapioca Starch, Colloidal Anhydrous Silica

Use Suggestion

Adults take 1 capsule daily or as prescribed by your healthcare practitioner.

Store below 25° in a cool, dry, dark place.

Cautions

For Practitioner Dispensing Only
This product contains Pyridoxal-5-Phosphate which may be dangerous when used in large amounts or for a long time.
If symptoms persist consult your healthcare practitioner.
Vitamin supplements should not replace a balanced diet.

Known Side Effects
In doses typically administered for therapeutic purposes, 5-MTHF is considered non-toxic. At doses over 10mg daily, gastrointestinal complaints, insomnia, irritability, and fatigue have been reported.
Whilst some concern exists that supplementation with high doses of folic acid could mask a vitamin B12 deficiency, supplementation with 5-MTHF appears to sidestep this potential problem. Since 5-MTHF can only be converted to 5,10-methylenetetrahydrofolate (involved in DNA synthesis) after participating in homocysteine recycling with vitamin B12, 5-MTHF will not mask a B12 deficiency.

Medication Interactions
The activity of various B vitamins may affect, or be affected by, the presence of certain medications, including anticonvulsant and anti-inflammatory medications. Qualified consultation is advised when using these concomitantly.